The nurse is instructing a client on the cause of bipolar disorder. Which neurotransmitters will the nurse describe as contributing to the manic phase of this disorder?

Standard Text: Select all that apply.
1. Excessive glutamate
2. Excessive norepinephrine
3. Deficiency of gamma-aminobutyric acid
4. Deficiency of dopamine
5. Excessive serotonin


Correct Answer: 1,2,3
Rationale 1: Mania may involve an excess of excitatory neurotransmitters such as glutamate.
Rationale 2: Mania may involve an excess of excitatory neurotransmitters such as norepinephrine.
Rationale 3: Mania may involve a deficiency of inhibitory neurotransmitters such as gamma-aminobutyric acid (GABA).
Rationale 4: Dopamine is not associated with the manic phase of bipolar disorder.
Rationale 5: Serotonin is not associated with the manic phase of bipolar disorder.
Global Rationale: Mania may involve an excess of excitatory neurotransmitters such as glutamate and norepinephrine along with a deficiency of inhibitory neurotransmitters such as gamma-aminobutyric acid (GABA). Dopamine and serotonin are not associated with the manic phase of bipolar disorder.

Nursing

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