A patient with a bacteremia identified as E. meningoseptica infection was placed on intravenous penicillin; however, the patient did not improve after 5 days. Which one of the following state-ments explains these findings?
a. The dose was abbreviated and therefore did not have time to work.
b. The patient is most likely allergic to peni-cillin and is not responding.
c. Penicillin is ineffective against this or-ganism.
d. An aminoglycoside should be given along with the penicillin to increase its effects.
C
The species considered in this chapter are frequently resistant to <-lactams, including penicillins, cephalosporins and carbapenems, and aminoglycosides commonly used to treat infections caused by other gram-negative bacilli; therefore penicillin would be ineffective against this organism.
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