Which statements are true regarding opioid receptors? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected
1. Opioid blockers such as naloxone (Narcan) inhibit both the mu and kappa receptors.
2. Some opioids stimulate a particular receptor; others block a receptor.
3. Opioid blockers such as naloxone (Narcan) stimulate both the mu and kappa receptors.
4. Opioids interact with mu (types one and two) and kappa receptors.
5. Opioids interact with sigma, delta, and epsilon receptors only.
Correct Answer: 1, 2, 4
Rationale 1: Opioid blockers such as naloxone (Narcan) inhibit both the mu and kappa receptors.
Rationale 2: Some opioids stimulate a particular receptor; others block a receptor.
Rationale 3: Opioid blockers such as naloxone (Narcan) inhibit both the mu and kappa receptors.
Rationale 4: Opioids interact with at least six types of receptors: mu (types one and two), kappa, sigma, delta, and epsilon.
Rationale 5: Opioids interact with at least six types of receptors: mu (types one and two), kappa, sigma, delta, and epsilon.
Global Rationale: Opioid blockers such as naloxone (Narcan) inhibit both the mu and kappa receptors. Some opioids stimulate a particular receptor; others block a receptor. Opioids interact with at least six types of receptors: mu (types one and two), kappa, sigma, delta, and epsilon.
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