What agents are used primarily to treat cardiac-related conditions? (Select all that apply.)
A) Nonselective adrenergic blocking agents
B) Nonselective alpha-adrenergic blocking agents
C) Alpha1-selective adrenergic blocking agents
D) Nonselective beta-adrenergic blocking agents
E) Beta1-selective adrenergic blocking agents
A, D, E
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Drugs that block both alpha- and beta-adrenergic receptors are primarily used to treat cardiac-related conditions. Phentolamine, a nonselective alpha-adrenergic blocking agent, is used to treat extravasation of IV norepinephrine or dopamine and hypertension related to a pheochromocytoma. Alpha1-selective adrenergic blocking agents are used for treatment of hypertension and benign prostatic hyperplasia. The beta-adrenergic blocking agents are used to treat cardiovascular problems (hypertension, angina, migraine headaches) and to prevent reinfarction after myocardial infarction. Beta1-selective adrenergic blocking agents are used for treating hypertension, angina, and some cardiac arrhythmias.
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