In the renin-angiotensin-aldosterone pathway that regulates blood pressure, renin is controlled in the following ways EXCEPT
A) Juxtaglomerular cells themselves can sense pressure changes and release renin when blood pressure declines.
B) Decreases in blood pressure activate sympathetic neurons in the medulla oblongata, triggering renin secretion.
C) Macula densa cells in the wall of the distal tubule respond to a decrease in urine flow and Na+ delivery by releasing a paracrine signal that leads to renin secretion.
D) Decreased perfusion of the lung leads to the production of angiotensin-converting enzyme, or ACE, that directly leads to renin secretion.
Answer: D
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