What is the action of amiodarone (Cordarone), a class III agent used to treat cardiac dysrhythmias?
a. It acts as a myocardial depressant by inhibiting sodium ion movement.
b. It prolongs the duration of the electrical stimulation on cells and the refractory time between electrical impulses.
c. It acts as a beta-adrenergic agent.
d. It slows the rate of electrical conduction and prolongs the time between contractions.
ANS: D
Class I antidysrhythmic drugs act as a myocardial depressant by inhibiting sodium ion movement. Class II antidysrhythmic drugs act as beta-adrenergic agents. Class III agents slow the rate of electrical conduction and prolong the time between contractions. Class IV antidysrhythmic drugs prolong the duration of the electrical stimulation on cells and the refractory time between electrical impulses.
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