What system is used for excision repair in E. coli, what are its components, and what do they specifically do in the process?

What will be an ideal response?


Ans: Excision repair in E. coli is done by the uvr system. A combination of the proteins UvrA and UvrB recognizes DNA damage, upon which UvrA dissociates and UvrC attaches. UvrBC has endonuclease activity to remove a portion of the damaged strand. UvrD is a helicase that unwinds the DNA to allow the excised strand to be removed.

Biology & Microbiology

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