Imagine that the DNA replication error rate for a strain of bacterium that has a defective repair mechanism is 1 in 10 million. If the cell's genome is 5 million nucleotide pairs, how often will the genome sustain a mutation in this strain, keeping in
mind that both strands of a DNA molecule are replicated at once?
A) four times per cell division
B) once per cell division
C) once every five cell divisions
D) once every ten cell divisions
E) twice per cell division
Answer: B
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Assume that an mRNA molecule beginning with an AUG is made that is complementary to this DNAsequence:3
'?CTTACATGGCATCC?5' See the genetic code table above. The second codon (counting the start codon as the first codon) directs incorporation of which amino acid in the polypeptide?
a. asparagine b. tyrosine c. arginine d. proline e. cysteine
The most common mutant allele of the PAH gene, which is responsible for the metabolic disorder PKU, has a SNP in the splice donor site of one intron. What is the simplest way to detect this allele?
A) PCR using genomic DNA as template and two primers, one on either side of the SNP, followed by gel electrophoresis B) PCR using genomic DNA as template and two primers, one complementary to the region containing the SNP, followed by gel electrophoresis C) PCR using two primers, one on either side of the SNP, followed by sequencing the PCR products D) Direct exome sequencing using a microarray E) Whole-genome sequencing
What type of inheritance fits the data in this pedigree?
A) sex-linked dominant
B) autosomal recessive
C) autosomal dominant
Sebum contains ________ which contributes to creating an inhospitable environment on the surface of the body
A) lysozyme B) collagens C) acids D) salts E) bile