Which explanation best indicates why barbiturates are rarely used to treat anxiety and insomnia?
1. They have a greater associated cost.
2. They have a high risk of producing an allergic response.
3. They are seldom effective.
4. They produce many serious adverse effects.
Correct Answer: 4
Rationale: Barbiturates were the drug of choice for anxiety and insomnia prior to the discovery of safer drug alternatives. They can be effective, and are not necessarily more expensive. Allergic reactions can occur, but are rare, and are not a primary reason they are no longer used for anxiety and/or insomnia.
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