Which of the following phenomena best accounts for the increased presence of leukocytes at the site of inflammation?
A)
Existing leukocytes stick to the epithelial cells and move along blood vessel walls.
B)
Increased numbers of leukocytes are released into circulation via cytokine stimulation.
C)
Leukocytes are osmotically drawn from circulation into the interstitial space as a result of swelling.
D)
Epithelium expresses leukocyte stimulation factors in response to cell injury.
Ans:
A
Feedback:
During inflammation, leukocytes accumulate at the point of epithelial contact in the processes of margination, adhesion, and transmigration. This is not directly achieved by a way of increased leukocyte production or release, nor by osmotic pressure. The epithelium does not produce leukocyte stimulation factors.
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