Codeine has a greater maximal ability to suppress cough when compared with dextromethorphan. What is the most appropriate description of codeine when compared to dextromethorphan?
1. Codeine is more efficacious.
2. Codeine is less potent.
3. Codeine is more potent.
4. Codeine is less efficacious.
1
Rationale 1: Codeine has a greater maximal effect than dextromethorphan; it is more efficacious than is dextromethorphan.
Rationale 2:Potency refers to the dosage of drug required to produce a certain magnitude of response, whereas efficacy is the magnitude of the maximum response to a drug.
Rationale 3:Potency refers to the dosage of drug required to produce a certain magnitude of response, whereas efficacy is the magnitude of the maximum response to a drug.
Rationale 4:Codeine has a greater maximal effect than does dextromethorphan;therefore,it is more efficacious than dextromethorphan.
Global Rationale: Codeine has a greater maximal effect than dextromethorphan; therefore, it is more efficacious than dextromethorphan. Potency refers to the dosage of drug required to produce a certain magnitude of response, whereas efficacy is the magnitude of the maximum response to a drug.
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