A patient with cerebral palsy who has been receiving baclofen [Lioresal] via gastrostomy tube for 3 months is admitted to the hospital for evaluation of new-onset seizures. What may the nurse suspect to be the cause of these seizures?
a. Baclofen toxicity
b. Common adverse effect of baclofen
c. Idiopathic causes related to disease process
d. Missed doses of baclofen
D
Baclofen does not appear to cause physical dependence, but abrupt discontinuation has been as-sociated with adverse reactions. Abrupt withdrawal of oral baclofen can cause visual hallucina-tions, paranoid ideation, and seizures and should be considered when a patient develops these symptoms. Seizures are not a symptom of baclofen toxicity.
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