After teaching a group of nursing students about diuretics, the instructor determines that the teaching was successful when the students identify which of the following as causing diuresis by increasing the density of filtrate in the glomerulus?
Select all that apply.
A) Amiloride
B) Torsemide
C) Ethacrynic acid
D) Mannitol
E) Urea
Ans: D, E
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Osmotic diuretics, like mannitol and urea, cause diuresis by increasing the density of the filtrate in the glomerulus. Amiloride is a potassium-sparing diuretic that acts to block the reabsorption of sodium in the kidney tubules, thereby increasing sodium and water in the urine. Torsemide and ethacrynic acid are loop diuretics that inhibit reabsorption of sodium and chloride in the distal and proximal tubules of the kidney and in the loop of Henle.
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