Where is the SRP receptor located in a cell?
A. in the membrane of the rough endoplasmic
reticulum
B. in the membrane of the Golgi apparatus
C. in the nuclear envelope
D. in the membrane of the lysosome
Answer Key: A
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In cancer cells one allele of the tumor suppressor gene p53 is frequently mutated so that the protein is inactive, not produced, or deleted
The other allele will usually have a normal sequence and the promoter remains intact but the gene is not expressed. Sequencing with sodium bisulfite modification of DNA can be used to detect which cytosines are methylated. If the cancer cell DNA is sequenced what would be the anticipated results? A. Cytosines in or near the promoter region will be methylated B. Cytosines in or near the promoter will not be methylated C. Cytosines in the coding region will have an increased mehtylation D. There will be no differences in the methylation pattern of the promoter of p53 from a cancer cell and a normal cell
The change in the developmental fates of
different cell lineages in response to signals from adjacent tissues is a. contact inhibition. b. ooplasmic localization. c. embryonic induction. d. pattern formation. e. all of these.
Match the membrane lipid group on the left with the correct type of membrane lipid on the right
A) proposed the protein-lipid-protein "sandwich" model of the cell membrane B) proposed the "unit membrane" model based on electron microscopy images of the "railroad track" pattern of membranes C) proposed the fluid mosaic model of the cell membrane D) described the chemical nature of the cell membrane E) created lipid monolayers from solubilized cell membrane lipids F) determined the 3D structure of a membrane protein demonstrating transmembrane segments G) created lipid bilayers from solubilized cell membrane lipids H) demonstrated that a biological membrane is a lipid bilayer 1) Davson and Danielli 2) Gorter and Grendel 3) J. David Robertson 4) Irving Langmuir 5) Unwin and Henderson 6) Charles Overton 7) Singer and Nicolson
An inhibitor of phosphodiesterase activity would have which of the following effects?
A) block the response of epinephrine B) decrease the amount of cAMP in the cytoplasm C) block the activation of G proteins in response to epinephrine binding to its receptor D) prolong the effect of epinephrine by maintaining elevated cAMP levels in the cytoplasm E) block the activation of protein kinase A