Discuss the role of copper in the disorders Menkes disease and Wilson's disease

What will be an ideal response?


Two rare genetic disorders affect copper status in opposite directions. In Menkes disease, the intestinal cells absorb copper, but cannot release it into circulation, causing a life-threatening deficiency. Treatment involves giving copper intravenously. In Wilson's disease, copper accumulates in the liver and brain, creating a life-threatening toxicity. Wilson's disease can be controlled by reducing copper intake, using chelating agents such as penicillamine, and taking zinc supplements, which interfere with copper absorption.

Nutritional Science

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What will be an ideal response?

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What will be an ideal response?

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