The client with Parkinsonism asks the nurse why vitamin B6 should be avoided. Which response would be most appropriate for the nurse?
1. "The vitamin is excreted in the feces and bile."
2. "The vitamin causes mental confusion and hallucinations in people with Parkinson disease."
3. "The vitamin reverses or antagonizes the therapeutic effects of some anti-Parkinson drugs"
4. "The vitamin increases the amount of dopamine entering the brain and promotes levodopa production."
Correct Answer: 3
Rationale 1: Vitamin B6, a water-soluble vitamin, is excreted in the urine.
Rationale 2: Mental confusion and hallucinations are not caused by vitamin B6.
Rationale 3: Vitamin B6 reverses the therapeutic effects of the anti-Parkinson drug levodopa.
Rationale 4: Vitamin B6 does not increase the amount of dopamine in the brain.
Global Rationale: This vitamin may reverse or antagonize the therapeutic effects of the antiparkinsonism drug levodopa because it reduces the amount of dopamine entering the brain by facilitating the breakdown of levodopa in peripheral circulation. It does not cause mental confusion and hallucinations. It is water soluble and is excreted in the urine.
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