At which point in the variable segments does the RAG-1/2 complex introduce a single-strand break into the DNA during somatic rearrangement?

A. Between the coding region and the conserved heptamer
B. Between the conserved heptamer and the 12-bp spacer
C. Between the 23-bp spacer and the conserved nonamer
D. Between the nonamer and 12-bp spacer
E. None of the above


A

Health & Biomechanics

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