Discuss the two main limitations on making inferences about language based on studies of people with specific lesions

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Naturally occurring lesions are often not easily localized to a discrete region of the brain, with no effects on other regions. For example, when hemorrhaging or insufficient blood flow (such as impairment due to clotting) causes lesions, the lesions also may affect other areas of the brain. Thus, many patients who show cortical damage also have suffered some damage in subcortical structures. This may confound the findings of cortical damage.

Researchers are able to study the linguistic function of patients only after the lesions have caused damage. Typically they are unable to document the linguistic function of patients before the damage.

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