Which statements describe the status of research concerning development of major depressive disorder (MDD) and bipolar disorder (BPD)?
Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. It is likely that gene manipulation will reduce the prevalence of both MDD and BPD in the near future.
2. Genes responsible for the development of BPD have been identified, but those responsible for MDD are still elusive.
3. Some regions of the genome have been identified as potentially containing the genes that make clients susceptible to these disorders.
4. It is becoming increasingly clear that genetics is a prime determinant for the development of these disorders.
5. Development of these disorders is thought to be a result of interaction between genetics and environment.
3,5
Rationale 1: Work is still being done to identify the genes responsible for the development of these disorders.
Rationale 2: No strong susceptibility gene or set of genetic markers for either disorder have been clearly identified.
Rationale 3: While many studies have been inconclusive, they have served to identify some specific regions of the genome where additional research should be done.
Rationale 4: While genetics is thought to play a part in susceptibility, there is no clear evidence of a strong genetic determinant.
Rationale 5: The complex interactions that occur in a client's life are thought to have a strong influence on whether a genetic susceptibility is expressed.
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