The MD has prescribed omeprazole. What class of medication is this? What is the basic mechanism of the drug? What other drugs are available in this class? What other groups of medications are used to treat GERD?
What will be an ideal response?
• Omeprazole is an acid pump or proton pump inhibitor.
• These drugs interrupt the action of the H+/K+-ATPase enzyme, which moves hydronium ions across parietal cell membranes in exchange for potassium ions, resulting in an inhibition of the secretion of HCl.
• Other proton pump inhibitors include lansoprazole, esomeprazole, and pantoprazole.
• Other drugs used to treat GERD include antacids, histamine-2 receptor antagonists, foaming agents, and prokinetic medications that increase gastric motility.
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