Within the transcription bubble, the 9 most recently added nucleotides in the newly synthesized RNA strand temporarily form a helix with the template DNA strand. How might transcription be affected if helix formation did not occur?
A. Rewinding the DNA molecule would be inhibited.
B. Unwinding the DNA molecule would be inhibited.
C. The position of the 5' end of the RNA would be unstable, inhibiting elongation.
D. The position of the 5' end of the RNA would be unstable, stimulating elongation.
E. The position of the 3' end of the RNA would be unstable, inhibiting elongation.
Answer: E
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