A client has all of the following family and personal factors. Which one greatly increases the risk for the client to develop respiratory problems?

A. The client has long-standing hypertension.
B. The client's father died of lung cancer at age 82.
C. The client's sister has a child with cystic fibrosis.
D. The client has a deficiency of alpha1-antitrypsin.


D
Alpha1-antitrypsin is an enzyme in the lungs that limits the activity of other protein- destroying enzymes in the lungs. Without this limitation, those protein-destroying enzymes break down the collagen and elastin in the lungs, dramatically increasing the risk for developing emphysema at an early age. Other types of severe pulmonary problems are also more common among individuals who are deficient in alpha1-antitrypsin.

Nursing

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