Explain how the conformational change in sigma factor regulates its ability to bind DNA
What will be an ideal response?
Ans: The N-terminal region of sigma factor is an autoinhibitory region that blocks DNA binding by binding to the DNA-binding region of the protein. When sigma factor binds to the core polymerase, the N-terminal domain moves away from the DNA-binding domain.
You might also like to view...
Antiestrogens can bind to estrogen receptor sites
a. without activation. b. without inhibition. c. and amplify the response. d. and prevent reception of hormone action. e. and increase growth of tumors.
Which of the following individuals would be
considered a carrier of a sex-linked recessive defect? a. a man with the defect b. a woman with the defect c. a father of a son with the defect d. the normal daughter whose father had the defect e. a son of two unaffected parents
In not more than three sentences, explain why a plant placed in a window grows toward the light. What will be an ideal response?
Immediate hypersensitivity is ________ mediated, and delayed type hypersensitivity is ________ mediated
a. antibody / cell b. cell / antibody c. Th1 / IgE d. IgG / Th2