A young couple visits the nurse practitioner prior to attempting to become pregnant. The husband states that his brother died of a severe infection at age 6 months

He never knew what was wrong, but his mother had him tested for gammaglobulins as a child. Based on theses statements the nurse would suspect which of the following disorders?
A) Severe neutropenia
B) X-linked agammaglobulinemia
C) Drug-induced thrombocytopenia
D) Aplastic anemia


Ans: B
Feedback: Based on the fact the mother of this individual had him tested for gammaglobulin as a child, his sibling probably had X-linked agammaglobulinemia. More than 10% of patients with X-linked agammaglobulinemia are hospitalized for infection at less than six months of age. Since the condition is X-linked it is important for the couple to undergo genetic testing. The child would have suffered from severe neutropenia only if there was evidence of bacterial or fungal infections. There is no evidence of drug-induced thrombocytopenia or aplastic anemia.

Nursing

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