Huntington disease is caused by expansion of the trinucleotide repeat region of the HD gene that results in the production of a Huntingtin protein with an expanded number of glutamines. An animal model with most features of this syndrome could be created by
A) adding a transgene containing a disease-causing mutant allele of the HD gene to a mouse or primate genome.
B) adding a transgene containing a wild-type copy of the HD gene to a mouse or primate genome.
C) knocking out both copies of the HD gene from a mouse or primate genome.
D) knocking out one copy of the HD gene from a mouse or primate genome.
A) adding a transgene containing a disease-causing mutant allele of the HD gene to a mouse or primate genome.
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