A patient comes to the clinic for a follow-up appointment. As the nurse reviews the patient's medications, the person states, "I don't think my lisinopril (Zestril) is as effective as it once was
" Which medication would the nurse be most concerned about reducing the effect of lisinopril? a. Spironolactone (Aldactone)
b. Furosemide (Lasix)
c. Verapamil (Calan)
d. Ibuprofen (Motrin)
D
Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the antihyper-tensive effects of ACE inhibitors.
Diuretics enhance the hypotensive effects of lisinopril, therefore the nurse should not be con-cerned if the patient is concurrently taking either spironolactone or furosemide.
Verapamil is not contraindicated in patients taking lisinopril.
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