Genetic testing of a placenta reveals mosaicism. What are the implications for the fetus?
Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. The fetus must also have mosaicism.
2. There should be no effects on the fetus.
3. Stillbirth is more common.
4. Fetal growth may be retarded.
5. The fetus will spontaneously abort prior to the 20th gestational week.
3,4
Rationale 1: In situations of confined placental mosaicism, the fetus is euploid.
Rationale 2: There may or may not be effects on the fetus.
Rationale 3: Stillbirth is more common in instances of placental mosaicism.
Rationale 4: Retardation of fetal growth can occur with placental mosaicism.
Rationale 5: Spontaneous abortion may occur, but these pregnancies do carry to term.
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