Deficiency in the production of AIRE results in _____. (Select all that apply.)

a. normal expression of tissue-specific proteins in the bone marrow and thymus
b. incomplete negative selection of developing T cells
c. the development of autoimmune B-cell and T-cell responses against endocrine glands and other tissues
d. death in infancy
e. the development of autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED).


b, c, e

Health & Biomechanics

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According to phenomenology, every experience comes loaded with meanings and qualities, none of which can be explained simply by a sense organ's reception of a stimulus.

Answer the following statement true (T) or false (F)

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An older adult who has been physically active throughout life is usually able to

A) gradually increase activity levels to improve heart function. B) maintain the same workout routine followed during middle age. C) reduce the level of physical activity when signs of bone loss are observed. D) gradually decrease the amount of exercise to protect bones and joints.

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Which sleep disorder is often attributed to jet lag?

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Health & Biomechanics