Genes are found in the same order for large stretches of the X chromosome in the rat and mouse genomes, indicating
A. occurence of aneuploidy.
B. formation of pseudogenes.
C. conservation of synteny.
D. conservation of neoteny.
Clarify Question
· What is the key concept addressed by the question?
· What type of thinking is required?
Gather Content
· What do you already know about synteny?
Consider Possibilities
· Consider the different answer options. Which can you rule out?
Choose Answer
· Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?
Reflect on Process
· Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
C. conservation of synteny.
Clarify Question
· What is the key concept addressed by the question?
o This question addresses synteny.
· What type of thinking is required?
o This question is asking you to take what you already know and apply it to this unfamiliar situation.
Gather Content
· What do you already know about synteny?
o Generally during evolution, chromosome rearrangements are common.
o Sometimes, however, the linear order of genes is the same in two species over long segments of chromosomes.
o This is called the conservation of synteny .
Consider Possibilities
· Consider the different answer options. Which can you rule out?
o Do genes in the same order indicate aneuploidy? No, aneuploidy would mean an extra or missing chromosome.
o Do genes in the same order indicate the formation of pseudogenes? No, pseudogenes are genes with mutations that are no longer functional.
o Do genes in the same order indicate conservation of neoteny? No, neoteny is a term meaning that juvenile characteristics are maintained in an adult animal.
Choose Answer
· Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?
o Do genes in the same order indicate conservation of synteny? Yes. The term synteny refers to a set of genes along a chromosome that are in the same order in two species.
Reflect on Process
· Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
o This question asked what is indicated by genes in the same order on the chromosomes of two species.
o The question required you to take what you already know and apply it to this unfamiliar situation.
o Did you remember that the conservation of gene order on a chromosome is called conservation of synteny?
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Fill in the blank(s) with correct word