The nurse is applying topical collagenase to a client. The nurse would assess the client for which of the following as a possible adverse reaction? Select all that apply
A) Mild pain
B) Urticaria
C) Numbness
D) Pruritus
E) Dermatitis
Ans: A, C, E
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Possible adverse reactions associated with the topical administration of collagenase (Santyl) include mild, transient pain; possible numbness; and dermatitis.
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