Which of the following factors differentiates chronic leukemias from acute leukemias?
A) Leukemic cells are disseminated throughout the body by the circulatory system.
B) The leukemic cells are more fully differentiated than in acute leukemias.
C) The prevalence among individuals with Down syndrome is high.
D) They are cancers of the hematopoietic progenitor cells.
Ans: B
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In contrast to acute leukemias, chronic leukemias are malignancies involving proliferation of more fully differentiated myeloid and lymphoid cells. Down syndrome is associated with acute leukemias, and both acute leukemias and chronic leukemias involve systemic distribution of leukemic cells.
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