Which preparation of antidiuretic hormone (ADH) is occasionally used to treat enuresis?

1. Bromocriptine (Cycloset)
2. Vasopressin (Pitressin)
3. Betamethasone (Celestone)
4. Desmopressin (Stimate)


4

Rationale 1:Bromocriptine (Cycloset) is used for the treatment of acromegaly (overproduction of growth hormone).
Rationale 2: Vasopressin (Pitressin) is a human ADH but only lasts 2–8 hours.
Rationale 3: Betamethasone (Celestone) is a glucocorticoid.
Rationale 4: A theory of treatment for enuresis is that these clients might benefit from ADH preparations for bladder control.Desmopressin is preferred as it has a duration of action of 20 hours.

Global Rationale: Desmospressin is a synthetic form ofhuman ADH that acts on the renal tubular cells to increase the reabsorption of water. It has a duration of action of up to 20 hours and is used to manage enuresis or bedwetting that occurs during the night.

Nursing

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