When heterogeneity of effects is high (statistically significant), the preferred meta-analytic approach is which of the following?

A) Abandon efforts to undertake a meta-analysis
B) Use a fixed effects analytic model
C) Use a random effects analytic model
D) Use a forest plot to display the extensiveness of heterogeneity to readers of the report


C
Feedback:
Statistical heterogeneity (diversity in effects across studies) is a major issue in meta-analysis, and affects decisions about using a fixed effects model (which assumes a single true effect size) or a random effects model (which assumes a distribution of effects). Heterogeneity can be examined using a forest plot.

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