Discuss the gene variant associated with folate status and its importance topericonceptional women.

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Some individuals have an increased need for folate due to specific gene variants involved in folate metabolism. These gene variants can impair the conversion of folate to its active form and increase folate requirement. One of the best-studied and most common gene variants affects 5,10-methylenetetrahydrofolate reductase (MTHFR) activity. This enzyme is responsible for production of the major circulating form of folate used by the body. The C677T allele of the gene that encodes for MTHFR produces an enzyme that has reduced activity. Women with this gene variant are at increased risk of having an NTD-affected newborn.

Nutritional Science

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Which disease is caused by a sequencing error in the structure of hemoglobin, which changes its shape and characteristics?

a. Diabetes b. Marasmus c. Phenylketonuria d. Sickle-cell anemia e. Hemolytic anemia

Nutritional Science

Which of the following would NOT be defined as a stroke or TIA?

a. Reduced cerebral blood flow b. An obstruction that clogs a blood vessel supplying oxygen to the brain c. A vessel in the brain that ruptures and decreases blood supply to the brain d. Plaque that builds up in the arteries supplying blood to the brain e. Any of these would fit the definition for stroke/TIA.

Nutritional Science

The recommended amount of prenatal weight gain is based upon:

A) maternal girth circumference. B) maternal blood pressure. C) maternal height and weight before pregnancy. D) maternal bone mineral density. E) maternal fasting blood sugar.

Nutritional Science

Which of the following is an example of water shifting due to hydrostatic pressure?

a. Loss of plasma volume due to heavy sweating b. Swelling of the feet and ankles when standing for a long period of time c. Swelling of cells due to high intracellular sodium concentrations d. All of the above

Nutritional Science