The nurse knows that which medication is considered the mainstay of pharmacological intervention in the client with tuberculosis?
1. Isoniazid
2. Pyrazinamide (PZA)
3. Rifampin (Rifadin, Rimactane)
4. Ethambutol (Myambutol)
Correct Answer: 1
Rationale 1: Isoniazid is considered the mainstay of treatment for tuberculosis.
Rationale 2: Pyrazinamide is an important medication but is not considered the primary drug in treatment of tuberculosis.
Rationale 3: Rifampin is an important medication but is not considered the primary drug in treatment of tuberculosis.
Rationale 4: Ethambutol is an important medication but is not considered the primary drug in treatment of tuberculosis.
Global Rationale: Although a patient may take many different drugs during the long treatment period, isoniazid is considered the prototype antituberculosis drug. The other medications are useful, but do not hold prototype status.
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