Which two-drug regimen would be appropriate for a patient with hypertension who does not have other compelling conditions?
a. Hydrochlorothiazide and nadolol
b. Hydralazine and minoxidil
c. Spironolactone and amiloride
d. Trichlormethiazide and hydrochlorothia-zide
A
When two or more drugs are used to treat hypertension, each drug should come from a different class. Hydrochlorothiazide is a diuretic and nadolol is a beta blocker, so this choice is appropriate. Hydralazine and minoxidil are vasodilators. Spironolactone and amiloride are potassium-sparing diuretics. Trichlormethiazide and hydrochlorothiazide are both thiazide diuretics.
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