A patient has been brought to the emergency department (ED) with a Stevens-Johnson rash. What might the nurse consider as a possible cause?
1. Target reaction to a drug
2. Allergic reaction to a drug
3. Paradoxical reaction to a drug
4. Idiosyncratic reaction to a drug
Answer: 2
Explanation: An allergic (hypersensitive) reaction occurs when an antibody-antigen response causes an extreme reaction in the body; for example, lamotrigiene (Lamictal) has been observed to cause Stevens-Johnson rash, an allergic response that can be fatal. Idiosyncratic reactions are unexpected and unpredictable. Paradoxical reactions have the opposite of the desired effect. A target effect is the desired reaction to a medication.
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