Which one of the following interactions is not a stabilizing force at the tertiary level of protein organization?
A. an ionic bond between a positively charged side chain and a negatively charged side chain
B. hydrophobic clustering of non-polar side chains in the interior of a protein
C. hydrogen bonding between a carbonyl oxygen of one peptide bond and an amide hydrogen of a nearby peptide bond
D. disulfide linkages between cysteine residues
E. van der Waals interactions between side chains in close proximity
Answer: C
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