A nursing student asks a nurse how antibacterials work. The nurse outlines the process, explaining that many antibacterials work by blocking bacterial DNA replication. The nurse knows further teaching is needed when the student states:
1. "Drugs inhibit the availability of precursor bases or nucleotides."
2. "Drugs can interact or bind with DNA, preventing the uncoiling or relaxation process."
3. "Drugs can bind to enzymes of DNA replication, halting the formation of new DNA strands."
4. "Drugs repair bacterial DNA damage."
Correct Answer: 4
Rationale 1: This is one of the ways in that antibacterials block bacterial DNA replication.
Rationale 2: This is one of the ways in that antibacterials block bacterial DNA replication.
Rationale 3: This is one of the ways in that antibacterials block bacterial DNA replication.
Rationale 4: Drugs that block bacterial DNA replication would block the repair of the DNA, not allow it.
Global Rationale: Drugs that block bacterial DNA replication would block the repair of the DNA, not allow it. Drugs block bacterial DNA replication by inhibiting synthesis of precursor bases or nucleotides, binding to bacterial DNA, and binding to the enzymes needed for replication.
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