The nurse is caring for a client with a very low platelet count. The nurse recognizes that a resurgence in the platelet count is most likely to occur in response to a higher circulating level of which substance?
1. Thrombopoietin
2. Colony-stimulating factors
3. An interferon
4. Erythropoietin
Correct Answer: 1
Rationale 1: Platelets are derived from megakaryocytes. Their production is driven by thrombopoietin.
Rationale 2: Colony-stimulating factors do not affect platelet production.
Rationale 3: Interferons do not affect platelet production.
Rationale 4: Erythropoietin does not affect platelet production.
Global Rationale: Platelets are derived from megakaryocytes. Their production is driven by thrombopoietin. Colony-stimulating factors do not affect platelet production. Interferons do not affect platelet production. Erythropoietin does not affect platelet production.
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