A nurse cares for a client who has a specific mutation in the a1AT (alpha1-antitrypsin) gene. Which action should the nurse take?

a. Teach the client to perform monthly breast self-examinations and schedule an annual mammogram.
b. Support the client when she shares test results and encourages family members to be screened for cancer.
c. Advise the client to limit exposure to secondhand smoke and other respiratory irritants.
d. Obtain a complete health history to identify other genetic problems associated with this gene mutation.


ANS: C
The a1AT gene mutation increases risk for developing early-onset emphysema. Clients should be advised to limit exposure to smoke and other respiratory irritants as a means of decreasing environmental influences that may aggravate an early onset of emphysema. This gene mutation does not promote cancer, nor does it occur with other identified genetic problems. The BRCA1 gene mutation gives the client a higher risk for developing breast cancer.

Nursing

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