Evidence-based guidelines for the treatment of septic shock include which of the following? (Select all that apply.)
a. Fluid resuscitation to maintain central venous pressure at 8 mm Hg or greater
b. Low-dose dopamine for renal protection
c. High-dose corticosteroids
d. Administration of activated protein C
e. Achieve central venous oxygen saturation of 70% or more
A, D, E
There is no evidence to support the use of dopamine; low-dose steroids are part of the sepsis management bundle.
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