A nurse cares for a client with autosomal dominant polycystic kidney disease (ADPKD). The client asks, "Will my children develop this disease?" How should the nurse respond?
a. "No genetic link is known, so your children are not at increased risk."
b. "Your sons will develop this disease because it has a sex-linked gene."
c. "Only if both you and your spouse are carriers of this disease."
d. "Each of your children has a 50% risk of having ADPKD."
ANS: D
Children whose parent has the autosomal dominant form of PKD have a 50% chance of inheriting the gene that causes the disease. ADPKD is transmitted as an autosomal dominant trait and therefore is not gender specific. Both parents do not need to have this disorder.
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