Tadalafil (Cialis) was prescribed 4 weeks ago for a man with erectile dysfunction. The patient also takes prazosin (Minipress) for hypertension. Which statement by the patient best demonstrates understanding of tadalafil (Cialis)?
a. "I can take this medication twice a day, just prior to intercourse."
b. "I have a little renal trouble, but I am on a higher dose so it is effective."
c. "I should take this medication with food."
d. "I should take this medication no more than once a day."
ANS: D
Tadalafil should be taken no more than once a day and without regard to meals.
Tadalafil has a half-life of 17.5 hours and should not be taken twice a day.
Men with moderate renal or hepatic insufficiency should take a reduced dosage. This patient may be confusing the actions of the tadalafil and prazosin.
Tadalafil is taken without regard to meals.
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