The nurse caring for a client in renal failure should question an order for which drug?
1. Ibuprofen (Advil) 800 mg three times daily
2. Erythromycin (E-Mycin) 500 mg four times daily
3. Aluminum hydroxide gel 30 mL every 4 hours as needed
4. Acetylsalicylic acid (aspirin) 162 mg daily
Correct Answer: 1
Rationale 1: Ibuprofen, an NSAID, is a nephrotoxic drug. Clients in renal failure have increased vulnerability to injury from nephrotoxic drugs.
Rationale 2: Erythromycin is not a nephrotoxic drug.
Rationale 3: Aluminum hydroxide gel is not a nephrotoxic drug.
Rationale 4: Acetylsalicylic acid is not nephrotoxic at low-to-usual doses.
Global Rationale: Ibuprofen, an NSAID, is a nephrotoxic drug. Clients in renal failure have increased vulnerability to injury from nephrotoxic drugs. Erythromycin and aluminum hydroxide gel are not nephrotoxic drugs. Acetylsalicylic acid is not nephrotoxic at low-to-usual doses.
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