When caring for a client receiving a methotrexate infusion, the nurse should:
a. administer leucovorin immediately after the infusion of methotrexate.
b. increase the client's intravenous fluids, if the specific gravity falls below 1.010.
c. discontinue the infusion, if nausea and vomiting develop.
d. premedicate the client with prednisone to prevent hemorrhagic cystitis.
ANS: A
Feedback
A Correct: This is the appropriate nursing action. Leucovorin competes with methotrexate at the cellular level to decrease uric acid levels.
B Incorrect: This is not specific to methotrexate.
C Incorrect: The med should not be discontinued but rather an antiemetic may be prescribed.
D Incorrect: Methotrexate is not associated with hemorrhagic cystitis.
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