Discuss the effect of acid and base shifts on electrolyte balance.

What will be an ideal response?


Hydrogen ions and bicarbonate are both electrolytes. Acid–base changes will therefore affect concentrations of other electrolytes in both ECF and intracellular fluid (ICF). For example, movement of HCO3- to the plasma requires the exchange of another negatively charged ion so that electroneutrality is maintained. Chloride is the ion that moves in the opposite direction of HCO3-. Changes in potassium, chloride, and sodium may accompany acid–base disorders.

Nutritional Science

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