A nursing instructor is preparing a class about cephalosporins for a group of nursing students. When describing progression from first-generation to fourth-generation cephalosporins, which of the following would the instructor include as the result?
Select all that apply.
A) An increase in the sensitivity of gram-negative microorganisms
B) A decrease in the sensitivity of gram-negative microorganisms
C) An increase in the sensitivity of gram-positive microorganisms
D) A decrease in the sensitivity of gram-positive microorganisms
E) An increase in the sensitivity of viral microorganisms
Ans: A, D
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In general, progression from first-generation to fourth-generation cephalosporins shows an increase in the sensitivity of gram-negative microorganisms and a decrease in the sensitivity of gram-positive microorganisms.
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