What are the processes involved in the maturation of the ova?
What will be an ideal response?
The stem cells, or oogonia, have completed their mitotic divisions prior to birth, at which time there are about 2,000,000 primordial oocytes. They remain in a suspended state until puberty, at which time there are approximately 4,000,000. Each of the primary oocytes is located in the outer cortex of the ovary in clusters called egg nests. They are surrounded by a layer of follicular cells and are known as primordial follicles. At puberty, FSH stimulation causes growth of the primordial follicles. The primordial follicles become primary follicles, in which the cells enlarge and undergo repeated divisions, making a layer of cells around the oocyte. These layers nourish the oocyte. Only a few primary follicles progress to secondary follicles, with thickened walls and an increased amount of follicular fluid. By days 8 to 10 in the cycle, a single secondary follicle is prepared to become a tertiary follicle, or mature mature ovarian follicle. It is this follicle that will ovulate on day 14.
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What will be an ideal response?