Cancer cells retain the IF proteins from the tissue of origin even after metastasizing to other tissues. How is this important in the diagnosis and treatment of cancer?
What will be an ideal response?
Answer: Evidence for metastasis (movement of cancer cells to other tissues) of a tumor usually indicates a poorer prognosis. Treatment strategies are based on the cancer cell origin, which is revealed by determining the type of intermediate filaments expressed.
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Avidin binds biotin with a Kd of ~10?15 mol/L. A protein of interest can be covalently linked to biotin and subsequently isolated by incubating with beads coated with avidin
If the concentration of biotinylated protein is 10-8 M at the beginning of the assay and the beads provided an excess of avidin-binding sites, then one could expect the beads to bind: A. a small fraction of the protein in the sample. B. approximately half the protein in the sample. C. almost all of the protein in the sample. D. 10–15 mol of protein per 1 mL of sample. E. This cannot be predicted.
When entering a newly generated DNA sequence into the Basic Local Alignment Search Tool (BLAST), a researcher can:
A. identify orthologs. B. assign tentative function to a protein. C. identify restriction enzyme sites. D. identify orthologs and assign tentative function to a protein. E. identify orthologs and identify restriction enzyme sites.
The centrosomes are a part of the chromosome that help in chromosome movement during mitosis and meiosis
Indicate whether the statement is true or false
Which structure would allow you to move your hand away from a hot burner after touching it?
A) sensory neuron B) interneuron C) motor neuron D) glial cell